This course examines how Singapore harnesses specific AI strategies (e.g. based on generative, predictive, embodied and emotion AI paradigms) to efficiently and effectively address healthcare needs by (i) improving the use of reliable health information by the public and health professionals to facilitate education and research; (ii) enhancing health technology for early detection, accurate and rapid diagnosis, and the discovery of new, safe and effective treatments; and (iii) integrating healthcare management and support for monitoring patients’ health condition and emotions. The prospects, limitation and possible mitigation of these AI technologies, and their governance, ethics and regulatory framework will be discussed.